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Molecular analysis of WT1 and KIT mutations in patients from an Indian population with de novo acute myeloid leukemia: determination of incidence, distribution patterns, and report of a novel KIT mutation

✍ Scribed by Ahmad, Firoz; D'Souza, Wilma; Mandava, Swarna; Ranjan Das, Bibhu


Book ID
125487726
Publisher
Informa plc
Year
2011
Tongue
English
Weight
938 KB
Volume
52
Category
Article
ISSN
1042-8194

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Mutations of NPM1 gene in de novo acute
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## Abstract Mutations in the nucleophosmin (__NPM1__) gene have been recently described to occur in about one‐third of acute myeloid leukaemias (AMLs) and represent the most frequent genetic alteration currently known in this subset, specially in those with normal karyotype. This study explored the