Mutations of NPM1 gene in de novo acute
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Firoz Ahmad; Swarna Mandava; Bibhu Ranjan Das
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Article
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2009
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John Wiley and Sons
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English
β 371 KB
## Abstract Mutations in the nucleophosmin (__NPM1__) gene have been recently described to occur in about oneβthird of acute myeloid leukaemias (AMLs) and represent the most frequent genetic alteration currently known in this subset, specially in those with normal karyotype. This study explored the