Molecular analysis of familial polyposis coli
β Scribed by Yuchio Yanagawa; Takehiko Sasazuki
- Publisher
- Nature Publishing Group
- Year
- 1990
- Tongue
- English
- Weight
- 159 KB
- Volume
- 35
- Category
- Article
- ISSN
- 1435-232X
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π SIMILAR VOLUMES
Two cases of hepatocellular carcinoma in patients with familial polypoais coli (FPC) have recently been reported in the literature. Hepatoblastoma was also reported in five children with maternal ancestors with FPC. We report a case of hepatoblastoma in a female infant whose father has FPC as furthe
## Development of one hundred or more adenomas in the colon and rectum is diagnostic for the dominantly inherited, autosomal disease Familial Adenomatous Polyposis (FAP). It is possible to identify a mutation in the Adenomatous Polyposis Coli (APC) gene in approximately 80% of the patients, and alm