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Molecular analysis of a novel hereditary C3 deficiency with systemic lupus erythematosus

✍ Scribed by Hiroshi Tsukamoto; Takahiko Horiuchi; Hisashi Kokuba; Shonosuke Nagae; Hiroaki Nishizaka; Takuya Sawabe; Shin-ichi Harashima; Daisuke Himeji; Takako Koyama; Junji Otsuka; Hiroki Mitoma; Yasutaka Kimoto; Chinami Hashimura; Etsuko Kitano; Hajime Kitamura; Masutaka Furue; Mine Harada


Book ID
116290178
Publisher
Elsevier Science
Year
2005
Tongue
English
Weight
345 KB
Volume
330
Category
Article
ISSN
0006-291X

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Homozygous hereditary C1q deficiency and
✍ Jason H. Slingsby; Peter Norsworthy; Glen Pearce; Akshay K. Vaishnaw; Helen Issl πŸ“‚ Article πŸ“… 1996 πŸ› John Wiley and Sons 🌐 English βš– 739 KB

Objective. To describe a new kindred with Clq deficiency and to identify the molecular lesions responsible for complete functional Clq deficiency in this and 2 other previously described kindreds. Methods. The A-, B-, and C-chain genes of Clq were amplified by polymerase chain reaction, cloned, and