Molecular analysis at the hisD3052 allele of S. typhimurium of mutations induced by aromatic amines, activated by mixed-function oxidases from plants

Molecular analysis of mutations induced

Molecular analysis of mutations induced by the intercalating agent ellipticine at the hisd3052 allele of salmonella typhimurium TA98

✍ Dr. David M. Demarini; Amal Abu-Shakra; Ranjan Gupta; Linda J. Hendee; Jessie G. 📂 Article 📅 1992 🏛 John Wiley and Sons 🌐 English ⚖ 687 KB

We have used DNA colony hybridization, the polymerase chain reaction (PCR), and direct DNA sequencing to determine the mutations induced by the intercalating agent ellipticine in Salmonella typhimurium TA98 in the presence of S9. O f 400 ellipticine-induced revertants that were selected at a mutant