Molecular Analysis and Genome Discovery, Second Edition

• Year: 2011
• Tongue: English
• Leaves: 314
• Category: Library

✦ Synopsis

Molecular Analysis and Genome Discovery, Second Edition is a completely revised and updated new edition of this successful book. The text provides a comprehensive overview of recent developments in the fast moving field of molecular based diagnostics of disease markers. Key concepts and applications are provided alongside practical information on current techniques currently being researched and developed. Each chapter offers an up-to-date analysis of the subject encompassing the very latest technology platforms and is an essential reference for researchers in the field looking for an up-to-date overview of the subject. The book will also be an indispensable resource for those working in the biotechnology and pharmaceutical industries. New for this edition: chapters on Genotyping through Mutation Detection; Differential Gene Expression; Haplotyping and Molecular Profiling.Content:
Chapter 1 Overview of Genotyping (pages 1–23): Monica Bayes and Ivo Glynne Gut
Chapter 2 DNA Chip Analysis in Genome Discovery (pages 24–42): Ross N. Nazar and Jane Robb
Chapter 3 qPCR, Theory, Reliability and Use in Molecular Analysis (pages 43–55): Jamie Murphy and Stephen A. Bustin
Chapter 4 DNA Analysis in Droplet?Based Microfluidic Devices (pages 56–80): Pinar Ozdemir and Yonghao Zhang
Chapter 5 High?Resolution Melt Profiling (pages 81–113): Steven F. Dobrowolski and Carl T. Wittwer
Chapter 6 Massively Parallel Sequencing (pages 114–134): Tracy Tucker, Marco Marra and Jan M. Friedman
Chapter 7 Aptamers for Analysis: Nucleic Acids Ligands in the Post?Genomic Era (pages 135–174): Pedro Nadal, Alessandro Pinto, Marketa Svobodova and Ciara K. O'sullivan
Chapter 8 Use of Nanotechnology for Enhancing of Cancer Biomarker Discovery and Analysis: A Molecular Approach (pages 175–192): Farid E. Ahmed
Chapter 9 Chip?Based Proteomics (pages 193–218): Julian Bailes, Andrew Milnthorpe, Sandra Smieszek and Mikhail Soloviev
Chapter 10 Antibody Microarrays in Proteome Profiling (pages 219–243): Mohamed Saiel Saeed Alhamdani and Jorg D. Hoheisel
Chapter 11 Biomarker Detection and Molecular Profiling by Multiplex Microbead Suspension Array Based Immunoproteomics (pages 244–270): V. V. Krishhan, Imran H. Khan and Paul A. Luciw
Chapter 12 Mass Spectrometry in Metabolomics (pages 271–298): William J. Griffiths and Yuqin Wang