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Molecular alterations in the tumor suppressor gene WWOX in oral leukoplakias

✍ Scribed by Flávio Juliano Pimenta; Gabriela Tavares Cordeiro; Luiz Gustavo Garcia Santos Pimenta; Michelle Beatriz Viana; Joyce Lopes; Marcus Vinícius Gomez; C. Marcelo Aldaz; Luiz De Marco; Ricardo Santiago Gomez


Book ID
113832944
Publisher
Elsevier Science
Year
2008
Tongue
English
Weight
334 KB
Volume
44
Category
Article
ISSN
1368-8375

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## Abstract Oral squamous cell carcinoma (OSCC) is the most common malignant neoplasm of the oral cavity, representing ˜90% of all oral carcinomas and accounting for 3–5% of all malignancies. The __WWOX__ gene (WW‐domain containing oxidoreductase) is a candidate tumor suppressor gene located at 16q

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