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Modulatory role of the endogenous nitric oxide synthase inhibitor, asymmetric dimethylarginine (ADMA), in morphine tolerance and dependence in mice

✍ Scribed by Ozgur Gunduz; Cetin Hakan Karadag; Ahmet Ulugol

Publisher
Springer
Year
2010
Tongue
English
Weight
255 KB
Volume
117
Category
Article
ISSN
1435-1463

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Inflammation is an important determinant
Inflammation is an important determinant of levels of the endogenous nitric oxide synthase inhibitor asymmetric dimethylarginine (ADMA) in acute liver failure
✍ Rajeshwar P. Mookerjee; R. Neil Dalton; Nathan A. Davies; Stephen J. Hodges; Cha πŸ“‚ Article πŸ“… 2007 πŸ› John Wiley and Sons 🌐 English βš– 165 KB

Acute liver failure (ALF) is characterized by rapid progressive organ failure and poor outcome. The pathophysiology of multiorgan dysfunction in ALF remains unclear but increased systemic inflammatory response is believed to be an important determining factor. Asymmetric dimethylarginine (ADMA), an