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Modulatory role of nitric oxide and cyclooxygenase enzyme pathway in LPS-mediated hyperalgesia

✍ Scribed by Naveen K. Jain; C. S. Patil; Shrinivas K. Kulkarni; Amarjit Singh

Book ID
119892528
Publisher
Springer
Year
2001
Tongue
English
Weight
196 KB
Volume
9
Category
Article
ISSN
0925-4692

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## Abstract The inhibitory effects of inotilone and methylinotilone on the induction of inducible nitric oxide synthase (iNOS) and cyclooxygenase‐2 (COX‐2) in murine RAW 264.7 cells activated with LPS were investigated. The results show that both hydroxyl groups on the benzene ring of the inotilone