Modulatory role of catecholamines in the transsynaptic expression of c-fos in the rat medial prefrontal cortex induced by disinhibition of the mediodorsal thalamus: a study employing microdialysis and immunohistochemistry

Disinhibition of the mediodorsal thalamu

Disinhibition of the mediodorsal thalamus induces Fos-like immunoreactivity in both pyramidal and GABA-containing neurons in the medial prefrontal cortex of rats, but does not affect prefrontal extracellular GABA levels

✍ Michael Bubser; Johanna M. De Brabander; Wia Timmerman; Matthijs G.P. Feenstra; 📂 Article 📅 1998 🏛 John Wiley and Sons 🌐 English ⚖ 183 KB 👁 2 views

Stimulation of the mediodorsal and midline thalamic nuclei excites cortical neurons and induces c-fos expression in the prefrontal cortex. Data in the literature data suggest that pyramidal neurons are the most likely cellular targets. In order to determine whether cortical interneurons are also imp