## Abstract Animal models are important tools to study the development of bone metastases and to evaluate strategies for their prevention and treatment. We here describe a new model in which tumour inoculation is achieved by injection of cancer cells into the femoral artery. This approach results i
โฆ LIBER โฆ
Modulatory effects of heparin and short-length oligosaccharides of heparin on the metastasis and growth of LMD MDA-MB 231 breast cancer cells in vivo
โ Scribed by Mellor, P; Harvey, J R; Murphy, K J; Pye, D; O'Boyle, G; Lennard, T W J; Kirby, J A; Ali, S
- Book ID
- 109999245
- Publisher
- Nature Publishing Group
- Year
- 2007
- Tongue
- English
- Weight
- 277 KB
- Volume
- 97
- Category
- Article
- ISSN
- 0007-0920
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We examined the effects of epidermal growth factor (EGF) on MDA-MB-468 cells to understand its mechanism of action in an EGF receptor-rich breast cancer cell line. EGF inhibited the growth of MDA-MB-468 cells with an IC 50 of 1.5 ฯฎ 0.5 nM, as determined by measurements of DNA content of cells in cul