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Modulation of β2 integrin phenotype, adhesion, chemotaxis, and oxidative burst of neutrophils by cyclosporine

✍ Scribed by M Scavuzzo; A Sagripanti; F Mosca; F Ambrogi

Book ID: 117575090
Publisher: Elsevier Science
Year: 2001
Tongue: English
Weight: 57 KB
Volume: 55
Category: Article
ISSN: 0753-3322
DOI: 10.1016/s0753-3322(00)00012-3

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## Objective: To investigate the role of intercellular adhesion molecule 1 (icam-1) and beta2 integrins in the production of superoxide (o2-) by c1q-stimulated human polymorphonuclear leukocytes (pmn). ## Methods: Pmn were pretreated with f(ab')2 fragments of monoclonal antibodies (mab) that bloc