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Modulation of voltage sensitivity by N-terminal cytoplasmic residues in human Kv1.2 channels

✍ Scribed by Anurag Varshney; Kavitha S.; M. Mathew


Publisher
Springer
Year
2002
Tongue
English
Weight
229 KB
Volume
31
Category
Article
ISSN
1432-1017

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The cloned human delayed rectifying K+ channel Kv2.1 (drk1) was expressed in clonal mouse fibroblasts (L-cells) and rat basophilic leukemia cells (RBL-1) by direct cytoplasmic microinjection of complementary RNA (cRNA). Within six hours, cells microinjected with Kv2.1 cRNA expressed a large sustaine