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Modulation of vascular smooth muscle cell alignment by cyclic strain is dependent on reactive oxygen species and P38 mitogen-activated protein kinase

✍ Scribed by Chen, Quanhai; Li, Wei; Quan, Zhiwei; Sumpio, Bauer E.

Book ID
122151419
Publisher
Elsevier Science
Year
2003
Tongue
English
Weight
735 KB
Volume
37
Category
Article
ISSN
1097-6809

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## Abstract Bovine aortic smooth muscle cell (SMC) phenotype can be altered by physical forces. This has been demonstrated by cyclic strain‐induced changes in proliferation and alignment. However, the intracellular coupling pathways remain ill defined. In the present study, we examined whether the