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Modulation of tumor necrosis factor related apoptosis-inducing ligand (TRAIL) receptors in a human osteoclast model in vitro

✍ Scribed by Stephen McManus; Estelle Chamoux; Martine Bisson; Sophie Roux


Publisher
Springer
Year
2011
Tongue
English
Weight
822 KB
Volume
17
Category
Article
ISSN
1360-8185

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## Abstract Tumor necrosis factor‐related apoptosis‐inducing ligand (TRAIL) has been shown to induce apoptosis in numerous transformed cell lines but not in most normal cells. Although this selectivity offers a potential therapeutic application in cancer, not all cancers are sensitive to TRAIL‐medi