Modulation of the volume-sensitive K+current in Ehrlich ascites tumour cells by pH
✍ Scribed by Charlotte Hougaard; Finn Jørgensen; Else Hoffmann
- Publisher
- Springer
- Year
- 2001
- Tongue
- English
- Weight
- 210 KB
- Volume
- 442
- Category
- Article
- ISSN
- 0031-6768
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📜 SIMILAR VOLUMES
## Abstract Recent evidence implicates the volume‐regulated anion current (VRAC) and other anion currents in control or modulation of cell cycle progression; however, the precise involvement of anion channels in this process is unclear. Here, Cl^−^ currents in Ehrlich Lettre Ascites (ELA) cells wer
After swelling in hyposmotic solution, Ehrlich ascites tumor cells shrink towards their original volume. Upon restoration of isosmolality (300 mOsM) the cells initially shrink but subsequently recover volume. This regulatory volume increase (RVI) is completely blocked when [Na+]o or [Cl-]o is reduce