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Modulation of the Heme Oxygenase HO-1 Expression by Hyperosmolarity and Betaine in Primary Rat Hepatocytes

✍ Scribed by Mohammad R. Lordnejad; Freimut Schliess; Matthias Wettstein; Dieter Häussinger

Book ID
115568698
Publisher
Elsevier Science
Year
2001
Tongue
English
Weight
238 KB
Volume
388
Category
Article
ISSN
0003-9861

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## Abstract We developed a retrovirus‐mediated human __heme oxygenase‐1__ (__HO‐1__) gene expression system and assessed the impact of heme on the inducibility of the __HO‐1__ gene in rat lung microvessel (RLMV) endothelial cells and in newborn Sprague‐Dawley (SD) rats. Overexpression of the __HO‐1