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Modulation of the development of bleomycin-induced fibrosis by deferoxamine

✍ Scribed by David B. Chandler; Thomas W. Butler; D.D. Briggs III; William E. Grizzle; James C. Barton; Jack D. Fulmer

Book ID: 113207137
Publisher: Elsevier Science
Year: 1988
Tongue: English
Weight: 817 KB
Volume: 92
Category: Article
ISSN: 0041-008X
DOI: 10.1016/0041-008x(88)90176-7

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## BACKGROUND. Bleomycin produces lung fibrosis in a wide variety of species. In humans, it can cause significant morbidity and mortality when used to treat malignancies such as lymphoma and testicular carcinoma. In rodents, it has been extensively used to study key mechanisms of lung injury and r