Modulation of sympathetic neurotransmission by neuropeptide Y Y2receptors in rats and guinea pigs
β Scribed by Erica K. Potter; Diana Tripovic
- Publisher
- Springer-Verlag
- Year
- 2006
- Tongue
- English
- Weight
- 306 KB
- Volume
- 173
- Category
- Article
- ISSN
- 0014-4819
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The respective distribution of neuropeptide Y Y 1 , Y 2 , Y 4 , and Y 5 receptor subtypes was investigated in rodents (rat and mouse), guinea pig, and primates (marmoset and vervet monkeys and human) brains, representing three orders of mammals. [ 125 I][Leu 31 ,Pro 34 ]PYY (total Y 1 -like; Y 1 , Y
## Background: Neuropeptide y (npy) is synthesized in sympathetic ganglia by specific mrna, to which rat probes are currently available. in the rat model, reserpine treatment increases npy mrna through a mechanism involving enhanced preganglionic activity. probes for npy mrna have been used exclusi