In this study, we investigated the effect of the extracellular matrix (ECM) secreted by vascular cells on proteoglycan (PG) synthesis by vascular smooth muscle cells in culture. PG synthesis of human aortic smooth muscle cells plated on plastic or the matrices derived from vascular endothelial cells
Modulation of smooth muscle cell behaviour by platelet-derived factors and the extracellular matrix
โ Scribed by Fiona E. Wren; Ana M. Schor; Seth L. Schor; Michael E. Grant
- Publisher
- John Wiley and Sons
- Year
- 1986
- Tongue
- English
- Weight
- 667 KB
- Volume
- 127
- Category
- Article
- ISSN
- 0021-9541
No coin nor oath required. For personal study only.
๐ SIMILAR VOLUMES
Four endothelial cell clones derived from adult bovine aorta were examined with respect to their proliferative characteristics in vitro. Three of these clones, derived in the absence of fibroblast growth factor (FGF), displayed variable basal proliferative rates. One of these non-FGF derived clones
We have examined the ability of transforming growth factor-pl (TGF-p1) and platelet-derived growth factor-BB (PDGF-BB) to regulate the expression of various integrins in cultured rabbit vascular smooth muscle cells (SMC). We found that expression of the a,p3 integrin complex was induced by both grow
Proliferation of smooth muscle cells from the pulmonary arteries and aortas of fetal calves is inhibited by heparin in vitro. This effect is reversible and dose dependent. Comparisons with effects of other polysaccharides indicate that only extensively sulfated polysaccharides inhibit proliferation
## Abstract Extracellular matrix (ECM) proteins can influence cell migration and differentiation in a variety of cell systems. Within the thymus, these molecules are heterogeneously distributed, and their physiological role is poorly understood. This prompted us to carry out __in vitro__ studies us