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Modulation of sinusoidal and canalicular elimination of bilirubin-glucuronides by rifampicin and other cholestatic drugs in a sandwich culture of rat hepatocytes

✍ Scribed by György Lengyel; Zsuzsa Veres; Regina Tugyi; László Vereczkey; Tünde Molnár; Hristos Glavinas; Péter Krajcsi; Katalin Jemnitz

Book ID
118087882
Publisher
John Wiley and Sons
Year
2008
Tongue
English
Weight
654 KB
Volume
38
Category
Article
ISSN
1386-6346

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Modulation of sinusoidal and canalicular
Modulation of sinusoidal and canalicular elimination of bilirubin-glucuronides by rifampicin and other cholestatic drugs in a sandwich culture of rat hepatocytes
✍ György Lengyel; Zsuzsa Veres; Regina Tugyi; László Vereczkey; Tünde Molnár; Hris 📂 Article 📅 2008 🏛 John Wiley and Sons 🌐 English ⚖ 654 KB

**Aim:** Drug‐induced hyperbilirubinemia has been shown to often be derived from modulation of the expression and activity of hepatobiliary transporters. In this study we examined the interactions of some therapeutic agents, which have been shown to cause cholestasis, with the elimination of bilirub