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Modulation of recombinant and native neuronal SK channels by the neuroprotective drug riluzole

✍ Scribed by Ying-Jun Cao; John C Dreixler; Jonathan J Couey; Khaled M Houamed


Book ID
114014925
Publisher
Elsevier Science
Year
2002
Tongue
English
Weight
190 KB
Volume
449
Category
Article
ISSN
0014-2999

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✍ Federica Albo; Massimo Pieri; Cristina Zona πŸ“‚ Article πŸ“… 2004 πŸ› John Wiley and Sons 🌐 English βš– 302 KB

## Abstract We investigated the interaction of riluzole, a therapeutic agent used in amyotrophic lateral sclerosis (ALS), with α‐amino‐3‐hydroxy‐5‐methyl‐4‐isoxazole propionic acid (AMPA) receptor channels in mouse spinal motor neurons in culture using whole‐cell patch‐clamp recording techniques. K