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Modulation of parathyroid hormone-sensitive adenylate cyclase in ROS 17/2.8 cells by dexamethasone 1,25-dihydroxyvitamin D3 and protein kinase C

✍ Scribed by Rao, L.G.; Wylie, J.N.


Book ID
123584193
Publisher
Elsevier Science
Year
1993
Tongue
English
Weight
667 KB
Volume
23
Category
Article
ISSN
0169-6009

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## Abstract 1,25‐Dihydroxyvitamin D~3~ (1,25(OH)~2~D~3~) treatment of osteoblastic cells was shown previously to attenuate Parathyroid hormone (PTH) response by inhibiting adenylyl cyclase (AC) activity. In this study, we have investigated the mechanism by which 1,25(OH)~2~D~3~ inhibits AC in rat o