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Modulation of Ornithine Decarboxylase Activity in Escherichia coli by Positive and Negative Effectors

✍ Scribed by Dimitri A. Kyriakidis, John S. Heller and E. S. Canellakis

Book ID
123655511
Publisher
National Academy of Sciences
Year
1978
Tongue
English
Weight
778 KB
Volume
75
Category
Article
ISSN
0027-8424

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Negative control of orinithine decarboxy
Negative control of orinithine decarboxylase and arginine decarboxylase by adenosine-3β€²:5β€²-Cyclic monophosphate in Escherichia coli
✍ Wright, Jonathan M. ;Boyle, Stephen M. πŸ“‚ Article πŸ“… 1982 πŸ› Springer 🌐 English βš– 718 KB

The polyamine biosynthetic enzymes, ornithine decarboxylase (EC 4.1.1.17) (ODC) and arginine decarboxylase (EC 4.1.1.19) (ADC), are negatively controlled by cAMP in Escherichia coli. The specific activities of ODC and ADC were determined in crude extracts prepared from E. coli strains carrying a mut