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Modulation of oestrogen receptor signalling by association with the activated dioxin receptor

✍ Scribed by Ohtake, Fumiaki; Takeyama, Ken-ichi; Matsumoto, Takahiro; Kitagawa, Hirochika; Yamamoto, Yasuji; Nohara, Keiko; Tohyama, Chiharu; Krust, Andree; Mimura, Junsei; Chambon, Pierre

Book ID
109891050
Publisher
Nature Publishing Group
Year
2003
Tongue
English
Weight
739 KB
Volume
423
Category
Article
ISSN
0028-0836

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The aryl hydrocarbon receptor (AhR) is a ligand-dependent transcription factor that mediates many of the biological and toxicological actions of a diverse range of chemicals, including the environmental contaminant 2,3,7,8-tetrachlorodibenzop-dioxin (TCDD, dioxin). Although no endogenous physiologic