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Modulation of noradrenaline-induced microvascular constriction by protein kinase inhibitors

✍ Scribed by Charlotte Fetscher; Husheng Chen; Rafael F. Schäfers; Gerhard Wambach; Gerd Heusch; Martin C. Michel

Book ID
105878297
Publisher
Springer-Verlag
Year
2001
Tongue
English
Weight
145 KB
Volume
363
Category
Article
ISSN
0028-1298

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Exposure of non-excitatory cells to the tyrosine kinase (PTK) inhibitors, genistein, herbimycin A, and tyrphostin, induced at least two families of K f currents. The first, a TEA-insensitive slow-inactivating K + current, is induced within 3 min following treatment with 140 m M genistein or 100 n M