Modulation of neurotrophic growth factors as a therapeutic strategy for neuropathic pain

Identification of a potent neurotrophic

Identification of a potent neurotrophic substance for ciliary ganglionic neurons in fetal calf serum as insulin-like growth factor II

✍ Toshiyuki Motoike; Klaus Unsicker 📂 Article 📅 1999 🏛 John Wiley and Sons 🌐 English ⚖ 190 KB

When fetal calf serum (FCS) alone is used as a trophic support for cultured chicken parasympathetic ciliary ganglionic (cCG) neurons, it does not show any survival-promoting effects on these neurons. When FCS is applied to heparin-affinity chromatography, however, potent survival-promoting activity