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Modulation of neuronal glutamate transporter rEAAC1 mRNA expression in rat brain by amitriptyline

✍ Scribed by Josefine Andin; Carina Stenfors; Svante B Ross; Jan Marcusson

Book ID
116753081
Publisher
Elsevier Science
Year
2004
Tongue
English
Weight
168 KB
Volume
126
Category
Article
ISSN
0169-328X

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## Background: The neurotransmitter glutamate is involved in fast excitatory synaptic transmission in the mammalian brain. glutamate released from presynaptic terminals must be removed rapidly from the synaptic cleft by high affinity, sodium-dependent glutamate transporters to keep the extracellula