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Modulation of N-type Ca2+ currents by moxonidine via imidazoline I1 receptor activation in rat superior cervical ganglion neurons

✍ Scribed by Young-Hwan Kim; Taick-Sang Nam; Duck-Sun Ahn; Seungsoo Chung

Book ID: 116301821
Publisher: Elsevier Science
Year: 2011
Tongue: English
Weight: 608 KB
Volume: 409
Category: Article
ISSN: 0006-291X
DOI: 10.1016/j.bbrc.2011.05.058

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Electrophysiological studies of the effects of test compounds on ion channel currents have been useful in the identification of novel therapeutic agents. Here, we examined the use of cultured superior cervical ganglion (SCG) neurons as a model system for the electrophysiological evaluation of N-type