Modulation of methylene carbon response intensity in long-range heteronuclear 2D NMR chemical shift correlation spectra

✍ Scribed by Miguel Salazar; Andrew S. Zektzer; Gary E. Martin

• Publisher: John Wiley and Sons
• Year: 1988
• Tongue: English
• Weight: 367 KB
• Volume: 26
• Category: Article
• ISSN: 0749-1581
• DOI: 10.1002/mrc.1260260107

✦ Synopsis

Several recent papers have dealt with the modulation of protonated carbon response intensities in long-range heteronuclear 2D NMR chemical shift correlation spectra. Expressions describing the one-tend modulation of the response intensity of the C-3 methylene resonance of 6,7dimethoxy-3,4dihydroisoquinoline, and the decoupling of this modulation afforded by a BIRD pulse located midway through the A2 refocusing delay, are presented with experimental confirmation. Long-range response intensities are related to the conventional heteronuclear chemical shift correlation spectrum optimized for transfer from the directly attached proton. KEY WORDS two-dimensional NMR 2D-NMR long-range heteronuclear correlation response intensity modulation modulation decoupling.