Modulation of matrix metalloproteinase production from human lung fibroblasts by type 4 phosphodiesterase inhibitors
β Scribed by Corinne A.E Martin-Chouly; Alexandra Astier; Claire Jacob; Marie-Pierre Pruniaux; Claude Bertrand; Vincent Lagente
- Book ID
- 116717407
- Publisher
- Elsevier Science
- Year
- 2004
- Tongue
- English
- Weight
- 322 KB
- Volume
- 75
- Category
- Article
- ISSN
- 0024-3205
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## Abstract Fibroblasts, a major constituent of gingival connective tissue, can produce immunoregulatory cytokines and proteolytic enzymes that may contribute to tissue destruction. In this study, we evaluated the production of matrix metalloproteinases (MMPs), tissue inhibitors of MMPs (TIMPs), an