Modulation of Kupffer cell activity by muramyl dipeptide ameliorates normothermic liver ischemia/reperfusion in rats
β Scribed by R Cursio; J Gugenheim; P Panaia-Ferrari; A Lasfar; M Tovey; S Chastanet; M.-C Saint-Paul; D Crenesse; J Mouiel
- Book ID
- 117238195
- Publisher
- Elsevier Science
- Year
- 1999
- Tongue
- English
- Weight
- 60 KB
- Volume
- 31
- Category
- Article
- ISSN
- 0041-1345
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## Abstract This work was performed to elucidate further the main cellular events underlying the protective effect of ischaemic preconditioning in an __in vivo__ rat liver model of 90βmin ischaemia followed by 30βmin reperfusion. A significant attenuation of the various aspects of postβischaemic in
The mechanisms of liver injury from cold storage and reperfusion are not completely understood. The aim of the present study was to investigate: 1) whether the inactivation of Kupffer cells (KCs) by gadolinium chloride (GadCl) modulates cold ischemia-reperfusion injury of rat liver; and 2) whether c