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Modulation of Kir4.1 and Kir5.1 by hypercapnia and intracellular acidosis

✍ Scribed by Haoxing Xu; Ningren Cui; Zhenjiang Yang; Zhiqiang Qu; Chun Jiang


Book ID
111119219
Publisher
Cambridge University Press
Year
2000
Tongue
English
Weight
249 KB
Volume
524
Category
Article
ISSN
0022-3751

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πŸ“œ SIMILAR VOLUMES


Modulation of the heteromeric Kir4.1–Kir
✍ N. Cui; L.R. Giwa; H. Xu; A. Rojas; L. Abdulkadir; C. Jiang πŸ“‚ Article πŸ“… 2001 πŸ› John Wiley and Sons 🌐 English βš– 240 KB

## Abstract Several inward rectifier K^+^ (Kir) channels are pH‐sensitive, making them potential candidates for CO~2~ chemoreception in cells. However, there is no evidence showing that Kir channels change their activity at near physiological level of P, as most previous studies were done using hig

Modulation of the heteromeric Kir4.1–Kir
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## Abstract The heteromeric Kir4.1–Kir5.1 channel is a candidate sensing molecule for central CO~2~ chemoreception. Since central CO~2~ chemoreception is subject to neural modulations, we performed studies to test the hypothesis that the Kir4.1–Kir5.1 channel is modulated by the neurotransmitters c