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Modulation of irinotecan with cyclosporine: a phase II trial in advanced colorectal cancer

โœ Scribed by Apurva A. Desai; Hedy L. Kindler; David Taber; Edem Agamah; Sridhar Mani; Kurombi Wade-Oliver; Mark J. Ratain; Everett E. Vokes

Publisher
Springer
Year
2005
Tongue
English
Weight
216 KB
Volume
56
Category
Article
ISSN
0344-5704

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Phase II trial of menogaril in advanced
Phase II trial of menogaril in advanced colorectal cancer
โœ Eduard E. Holdener; Wim W. Bokkel Huinink; Genevieve Decoster; Christian Ludwig; ๐Ÿ“‚ Article ๐Ÿ“… 1988 ๐Ÿ› Springer US ๐ŸŒ English โš– 262 KB

Menogaril, a new semisynthetic anthracycline antibiotic, was administered to 35 patients with advanced colorectal cancer. The drug was infused over 2 hr at a dose of 160 mg/sqm or 200 mg/sqm repeated every 4 weeks. Twenty-seven patients were evaluable for response and no objective responses were ach