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Modulation of intravenous cocaine effects by chronic oral cocaine in humans

โœ Scribed by Sharon L. Walsh; Kathleen A. Haberny; George E. Bigelow


Publisher
Springer
Year
2000
Tongue
English
Weight
158 KB
Volume
150
Category
Article
ISSN
0033-3158

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Cocaine (0.1 or 0.3 mg/kg/h) was infused continuously from osmotic minipumps during 14-day periods in three squirrel monkeys trained under a fixed-interval schedule of stimulus-shock termination. Chronic exposure to 0.1 mg/kg/h cocaine increased response rates during control sessions for two subject