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Modulation of interferon signaling by hepatitis C virus non-structural 5A protein: Implication of genotypic difference in interferon treatment

โœ Scribed by Sang-Min Kang; Seung-Jae Won; Gun-Hee Lee; Yun-Sook Lim; Soon B. Hwang


Book ID
113622182
Publisher
Elsevier Science
Year
2010
Tongue
English
Weight
913 KB
Volume
584
Category
Article
ISSN
0014-5793

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## Abstract Patients with low titer (<0.5 mEq/ml) of hepatitis C virus (HCV) genotype 2a achieve high and sustained response (SR) rates to interferon (IFN) monotherapy, but we also encounter patients who are resistant to therapy. We explored the relationship between response to IFN and virological