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Modulation of inducible nitric oxide synthase expression in astroglial cells

โœ Scribed by S.K. Park; D. Grzybicki; H.L. Lin; S. Murphy

Book ID
116037664
Publisher
Elsevier Science
Year
1994
Tongue
English
Weight
799 KB
Volume
33
Category
Article
ISSN
0028-3908

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โœ S. K. Park; S. Murphy ๐Ÿ“‚ Article ๐Ÿ“… 1994 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 658 KB

Lipopolysaccharide (LPS) or a combination of interleukin (IL)-lp and interferon (1FN)-y cause transcriptional induction of a calcium-independent nitric oxide synthase (NOS) in astrocytes and C6 glioma cells. LPS induction of NOS in C6 cells was evidenced by a small amount of nitrite accumulation as