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Modulation of IGF-2 expression during growth and differentiation of human neuroblastoma cells: Retinoic acid may induce IGF-2

✍ Scribed by Melino, Gerry; Stephanou, Anastasis; Annicchiarico-Petruzzelli, Margherita; Knight, Richard A.; Finazzi-Agro, Alessandro; Lightman, Stafford L.

Book ID: 122793335
Publisher: Elsevier Science
Year: 1993
Tongue: English
Weight: 583 KB
Volume: 151
Category: Article
ISSN: 0304-3940
DOI: 10.1016/0304-3940(93)90017-F

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## Abstract To investigate the alteration of nuclear matrix proteins (NMPs) during the differentiation of neuroblastoma SK‐N‐SH cells induced by retinoic acid (RA), differentiation markers were detected by immunocytochemistry and NMPs were selectively extracted and subjected to two‐dimensional gel