Infection Of A Naive (non-immune) Host With A Virus Elicits An Immediate Response Which Results In A Cascade Of Changes In The Host, Including An Interferon Response (innate Immunity). The Outcome Of This Interaction Is Influenced By The Genes Of The Virus As Well As The Genes Of The Host. Interestingly, Different Viruses Do It In Different Ways. Not Only Is There A Plethora Of Mechanisms Used By The Invading Organisms, But The Host Has Also Evolved A Great Variety Of Redundant And Robust Countermeasures. The Interplay Of Host And Virus Represents One Of The Most Significant Frontiers In Biology Today. A Clearer Understanding Of The Mechanisms Involved Will Arm Us With Better Strategies To Deal With Viruses, Including Emerging Pathogens And Potential Bioterrorism Agents. This Book Is Sure To Benefit Students, Scientists, And Physicians Working In The Areas Of Virology, Immunology, Microbiology, And Infectious Diseases. Pharmaceutical Industry Professionals Will Also Find Interest In This Illuminating Look Into Virus/host Interactions.--jacket. Viruses And The Innate Immune System / Megan L. Shaw, Peter Palese -- How Viruses Elicit Interferon Production / David E. Levy, Isabelle J. MariΓ© -- Gene Modulated By Interferons And Double-stranded Rna / Saumendra N. Sarkar, Gregory A. Peters, Ganes C. Sen -- Immunoevasive Strategies: Host And Virus / Markus Wagner, Shahram Misaghi, Hidde L. Ploegh -- Interferon Antagonists Of Influencza Viruses / Adolfo Garcia-sastre -- The Anti-interferon Mechanisms Of Paramyxoviruses / Nicola Stock, Stephen Goodbourn, Richard E. Randall -- The Strategy Of Conquest / Sunil J. Advani, Bernard Roizman -- Immunomodulation By Poxviruses / James B. Johnston, Grant Mcfadden -- Interferon Antagonists Encoded By Emerging Rna Viruses / Christopher F. Basler -- Viral Pathogenesis And Toll-like Receptors / Susan R. Ross -- Digesting Oneself And Digesting Microbes / Montrell Seay, Savithramma Dinesh-kumar, Beth Levine -- Genetic Variation In Host Defenses And Viral Infections / Eunhwa Choi, Stephen J. Chanock. Edited By Peter Palese. Includes Bibliographical References And Index.