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Modulation of heroin self-administration by neurohypophyseal principles

โœ Scribed by Jan M. Van Ree; David De Wied


Book ID
118322393
Publisher
Elsevier Science
Year
1977
Tongue
English
Weight
310 KB
Volume
43
Category
Article
ISSN
0014-2999

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Opiate tolerance by heroin self-administ
โœ Zheng-Xiong Xi; Gaohong Wu; Elliot A. Stein; Shi-Jiang Li ๐Ÿ“‚ Article ๐Ÿ“… 2004 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 455 KB

Functional MRI (fMRI) was employed to determine whether repeated heroin self-administration (SA) produces tolerance or sensitization in the brain of heroin-SA rats. Twelve rats were evenly divided into saline and heroin (0.06 mg/kg, 4 hr/day) SA groups. There was a progressive increase in drug-SA be