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Modulation of HERG affinity for E-4031 by [K+]o and C-type inactivation

โœ Scribed by Shimin Wang; Michael J Morales; Shuguang Liu; Harold C Strauss; Randall L Rasmusson


Book ID
117108330
Publisher
Elsevier Science
Year
1997
Tongue
English
Weight
698 KB
Volume
417
Category
Article
ISSN
0014-5793

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## Abstract Impairments in early information processing are a hallmark feature of diverse neuropsychiatric disorders including schizophrenia and Alzheimer's disease (AD). Several lines of evidence implicate a dysfunction of the cholinergic system in these disorders, particularly in AD where there i