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Modulation of hepatic gene expression and DNA methylation in furan treated Sprague–Dawley rats

✍ Scribed by Tao Chen; Kevin Hickling; Carolin Hamberger; Angela Mally; Kevin Chipman

Book ID
119381575
Publisher
Elsevier Science
Year
2009
Tongue
English
Weight
60 KB
Volume
189
Category
Article
ISSN
0378-4274

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Descending colon is the most unsitive segment of rat intestine and is at least as ynsitive as liver to the carcinogenic effectr of methylazoxymethanol acetate. To determine whether a relationship esistr between tumor induction and level of DNA methylation, we measured the levels of 7-methylguanine i