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Modulation of glutamate sensitivities by inhibitors of a protein kinase and a protein phosphatase in cultured rat Purkinje cells

โœ Scribed by Jiro Kasahara; Hiroyuki Sugiyama


Book ID
117476711
Publisher
Elsevier Science
Year
1998
Tongue
English
Weight
147 KB
Volume
247
Category
Article
ISSN
0304-3940

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Exposure of non-excitatory cells to the tyrosine kinase (PTK) inhibitors, genistein, herbimycin A, and tyrphostin, induced at least two families of K f currents. The first, a TEA-insensitive slow-inactivating K + current, is induced within 3 min following treatment with 140 m M genistein or 100 n M