Modulation of gene expression in hibernating arctic ground squirrels
β Scribed by Jun Yan; Brian M. Barnes; Franziska Kohl; Thomas G. Marr
- Book ID
- 116346589
- Publisher
- Elsevier Science
- Year
- 2008
- Tongue
- English
- Weight
- 64 KB
- Volume
- 148
- Category
- Article
- ISSN
- 1532-0456
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π SIMILAR VOLUMES
Hibernating animals are very tolerant of trauma to the central nervous system such that dramatic fluctuations in cerebral blood flow occur during hibernation and arousal without apparent damage. Indeed, it was demonstrated that Arctic ground squirrels (AGS) experience acute and severe systemic hypox
Heterothermic mammals such as ground squirrels tolerate ischemia and N-methyl-D-aspartate (NMDA) better than homeothermic mammals such as rats both in vivo and in vitro, and this tolerance is enhanced in the hibernating state. However, the cellular mechanisms underlying this tolerance remain unclear