Modulation of Forssman Glycosphingolipid Expression by Murine Macrophages: Coinduction with Class II MHC Antigen by the Lymphokines IL4 and IL6

Toxoplasma gondii down-regulates MHC cla

Toxoplasma gondii down-regulates MHC class II gene expression and antigen presentation by murine macrophages via interference with nuclear translocation of STAT1α

✍ Carsten G. K. Lüder; Wolfgang Walter; Barbara Beuerle; Markus J. Maeurer; Uwe Gr 📂 Article 📅 2001 🏛 John Wiley and Sons 🌐 English ⚖ 391 KB 👁 1 views

The obligate intracellular protozoan parasite Toxoplasma gondii is able to establish persistent infections within human and animal hosts. We have shown recently that T. gondii downregulates IFN-+ -induced MHC class II expression in murine bone marrow-derived macrophages (BMM ¶ ). As shown in this st