Modulation of experimental autoimmune neuritis in Lewis rats by oral application of myelin antigens
β Scribed by Stefanie Gaupp; Hans-Peter Hartung; Klaus Toyka; Stefan Jung
- Book ID
- 117337546
- Publisher
- Elsevier Science
- Year
- 1997
- Tongue
- English
- Weight
- 188 KB
- Volume
- 79
- Category
- Article
- ISSN
- 0165-5728
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π SIMILAR VOLUMES
Experimental autoimmune neuritis (EAN) is a CD4 1 Tcell-mediated inflammatory demyelinating disease of the peripheral nervous system (PNS) that serves as a model for Guillain-Barre Β΄syndrome (GBS) in humans. Various rat strains show different susceptibility to EAN. We examined PNS myelin-induced T-a
## Abstract A new and biphasic form of experimental autoimmune neuritis (EAN) is described in dark agouti rats (DA rats) and is inducible by a single immunization with bovine peripheral nerve myelin (BPM) in complete Freund's adjuvant (DAβEAN). Animals develop a mild episode of disease; after recov