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Modulation of Endothelial Cell Expression of ICAM-1, E-Selectin, and VCAM-1 by β-Estradiol, Progesterone, and Dexamethasone

✍ Scribed by Karim Elias Aziz; Denis Wakefield


Book ID
112239415
Publisher
Elsevier Science
Year
1996
Tongue
English
Weight
137 KB
Volume
167
Category
Article
ISSN
0008-8749

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Endothelial cells, as they normally exist in the vasculature as quiescent cells, perform several functions. In an inflammatory response, endothelial cells are activated to up-regulate a number of genes, including E-selectin (ELAM-l), VCAM-1, ICAM-1, interleukin (IL)-l, IL-8 and plasminogen activator