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Modulation of degranulation and superoxide generation in human neutrophils by unsaturated fatty acids of odd carbon numbers

✍ Scribed by Akiko Ishida-Okawara; Tomoko Tsuchiya; Hiroyuki Nunoi; Satoshi Mizuno; Kazuo Suzuki

Book ID: 117350713
Publisher: Elsevier Science
Year: 1996
Tongue: English
Weight: 651 KB
Volume: 1314
Category: Article
ISSN: 0167-4889
DOI: 10.1016/s0167-4889(96)00110-3

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## Abstract Cis‐unsaturated free fatty acids (FFA) at concentrations between 10 and 30 μM suppressed the superoxide respiratory burst induced in human neutrophils by the chemotactic peptide, N‐formylmethionyl‐leucyl‐phenylalanine (FMLP). Corresponding trans‐isomers had a reduced efficacy while satu