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Modulation of Compactness and Long-Range Interactions of Unfolded Lysozyme by Single Point Mutations

✍ Scribed by Julia Wirmer; Christian Schlörb; Judith Klein-Seetharaman; Ryoma Hirano; Tadashi Ueda; Taiji Imoto; Harald Schwalbe

Book ID
101529711
Publisher
John Wiley and Sons
Year
2004
Tongue
English
Weight
242 KB
Volume
116
Category
Article
ISSN
0044-8249

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✍ Bernhard Risse; Günter Stempfer; Rainer Rudolph; Günter Schumacher; Rainer Jaeni 📂 Article 📅 1992 🏛 Cold Spring Harbor Laboratory Press 🌐 English ⚖ 798 KB

## Abstract Point mutations in the gene of pyruvate oxidase from __Lactobacillus plantarum__, with proline residue 178 changed to serine, serine 188 to asparagine, and alanine 458 to valine, as well as a combination of the three single point mutations, lead to a significant functional stabilization