Modulation of clonal progression in B16F1 melanoma cells
β Scribed by J. F. Harris; A. F. Chambers; A. S. K. Tam
- Publisher
- Springer
- Year
- 1991
- Tongue
- English
- Weight
- 726 KB
- Volume
- 9
- Category
- Article
- ISSN
- 0262-0898
No coin nor oath required. For personal study only.
π SIMILAR VOLUMES
Four mouse BI6 melanoma subclones (G3.15, G3.5, G3.12 and G3.26) exhibit progressively greater growth capacity in vitro and in vivo. Previously, non-metastatic G3.15 cells were sequentially converted, in monolayer cultures, to the moderately-metastatic G3.5 cells, and then to a highly-metastatic G3.
## Abstract Three distinct disseminationβrelated phenotypes have been recognized in clones of the mouse B 16 melanoma based on __in vivo__ behavior: metastatic (spontaneously disseminating to the lungs from solid tumors), colonizing (capable of forming tumor colonies in the lungs following intraven