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Modulation of cisplatin-induced DNA cross-links in human tumour cells by regulations of glutathione content

✍ Scribed by Kai Zhang; May Chew; Peter Mack


Book ID
117667734
Publisher
Elsevier Science
Year
1999
Tongue
English
Weight
141 KB
Volume
35
Category
Article
ISSN
0959-8049

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Activation of Src, which has an intrinsic protein tyrosine kinase (PTK) activity, has been demonstrated in human solid tumors, such as colorectal and breast cancers. To investigate the role of activated Src in drug resistance, we evaluated the effect of v-src on the resistance to various anti-cancer